Skin biology advances as Oriflame presents new findings on Oripeptide-3 and ageing pathways

Findings from Oriflame’s long-term R&D programme show Oripeptide-3 supporting five key biological drivers of ageing, reinforcing its central role in NovAge+ skin longevity formulations.

New scientific data from Oriflame has brought renewed attention to the biological science of skin longevity as the company revealed new findings on Oripeptide-3, its patented bioactivating technology. The research, released nationally on 25 November 2025, marks a significant step in Oriflame’s long-term exploration of skin ageing, cellular health and the dynamics that influence the skin’s functional lifespan. Over nearly twenty years of research and development, the company has examined how biological pathways govern ageing, and the latest findings provide evidence of how Oripeptide-3 interacts with five core drivers that shape the ageing process.
The new insights form part of Oriflame’s continued study of how the skin responds to cellular stress, environmental exposure and changes in biological activity over time. Oripeptide-3 has long been positioned at the centre of the NovAge+ range and the company’s broader skin longevity platform. According to the latest research, the technology works closely with the skin’s natural biology, supporting its internal processes and helping maintain long-term functionality. The findings highlight its influence on cellular behaviour in areas linked to firmness, elasticity, clarity, radiance and resilience, reinforcing Oriflame’s view that the future of skincare lies in understanding the science of ageing rather than temporary correction.

Oriflame’s research indicates that Oripeptide-3 plays a role in reactivating aged cells to improve overall function. This supports the view that cellular slowing, which occurs naturally with age, can be addressed by technologies designed to enhance biological communication and stimulate renewal. The company reports that Oripeptide-3 contributes to improved firmness and elasticity through its support of DNA protection. This is an area widely recognised in skin biology, where DNA integrity influences the skin’s ability to maintain structure and recover from damage. Protecting and supporting genetic stability helps the skin remain resilient against daily stressors, which over time influence visible signs of ageing.
Another area highlighted in the research is protein quality. Oriflame notes that maintaining high protein quality is essential to reducing oxidative stress, one of the most prominent contributors to accelerated ageing. By supporting protein stability, Oripeptide-3 is positioned as a technology that helps improve radiance while also reducing the cumulative impact of everyday environmental stress. This contributes to the overall appearance of skin clarity and brightness, qualities often associated with healthy ageing.

Oriflame’s findings also indicate that Oripeptide-3 supports natural cellular renewal. Renewal cycles often slow down as skin matures, and this deceleration affects clarity, texture and vitality. The company’s research suggests that the technology helps stimulate natural renewal mechanisms, encouraging better turnover and improved skin tone. The support of cellular energy is another element noted in the new data. According to the company, maintaining adequate cellular energy is necessary for repair and daily defence, making it a crucial component of long-term skin health.
Speaking about the research, Lene Visdal-Johnsen, PhD and Director of Scientific Research and Innovation at Oriflame Global R&D, said that longevity has become the next major frontier in beauty. Her comments reflect a shift within the global skincare industry as brands invest in molecular and cellular research to understand how long-term ageing processes can be influenced through advances in biotechnology. She noted that Oriflame remains committed to leading this direction and emphasised the importance of innovations that work deeper within the skin’s biology rather than addressing only surface-level concerns.

Edyta Kurek, Senior Vice President and Head of Oriflame India and Indonesia, added that consumers are increasingly seeking formulations that deliver long-term benefits backed by scientific evidence. Her remarks pointed to a wider consumer shift toward skincare that supports long-term health rather than quick results. She stated that innovations such as Oripeptide-3 demonstrate the company’s commitment to advanced research and future-ready formulations that align with the expectations of an informed and scientifically aware consumer base.
The new findings not only reinforce the significance of Oripeptide-3 within the NovAge+ range but also underscore Oriflame’s position within the broader field of skin biology. By connecting long-term research with visible outcomes, the company aims to strengthen its role in developing formulations that address the deeper causes of ageing. The emphasis on molecular pathways, cellular protection and biological renewal positions Oriflame within a growing category of brands exploring longevity science.

Oriflame continues to expand its portfolio based on its Swedish roots, focusing on nature-inspired innovation and an approach that integrates scientific research with an understanding of well-being. With a presence in more than sixty countries and a sales force of approximately three million independent brand partners, the company maintains a strong global footprint. Its operating principles reflect a clear focus on respect for people and the environment, and its social and environmental policies inform its approach to innovation, production and long-term brand development.
With this latest research, Oriflame strengthens its commitment to exploring how skin longevity can be supported through targeted bioactive technology. The company’s focus on the biological drivers of ageing reflects its broader strategy to align skincare innovation with the deeper science of cell health, renewal and protection. As longevity becomes a central theme across the global beauty and wellness industry, Oriflame positions itself at the forefront of this shift, supported by data-driven insights and a research framework that spans decades.

At Prittle Prattle News, we honor your dedication and inventiveness led by showcasing you in a positive light. Under the direction of Editor-in-Chief Smruti Bhalerao, our platform is committed to disseminating powerful narratives that raise awareness and motivate change. For more important stories, follow us on LinkedIn, Instagram, and YouTub